Abstract
An extract from in vitro cultures of Curculigo orchioides grown as bulbils in shake flasks, afforded two new glucosides of substituted benzylbenzoate - curculigoside C (3) and curculigoside D (4) - together with two known compounds - curculigoside A (1) and curculigoside B (2). Their structures were elucidated on the basis of spectral evidence, in particular by using 2D NMR methods. Their vasoactive properties were assessed in isolated rat aortic rings.
Publication types
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Research Support, Non-U.S. Gov't
MeSH terms
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Animals
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Aorta / drug effects
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Benzyl Compounds / administration & dosage
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Benzyl Compounds / chemistry
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Benzyl Compounds / pharmacology
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Benzyl Compounds / therapeutic use
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Curculigo*
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Dose-Response Relationship, Drug
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Endothelium, Vascular / drug effects
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Glucosides / administration & dosage
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Glucosides / chemistry
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Glucosides / pharmacology
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Glucosides / therapeutic use
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Magnetic Resonance Spectroscopy
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Male
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Phytotherapy*
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Plant Extracts / administration & dosage
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Plant Extracts / chemistry
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Plant Extracts / pharmacology*
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Plant Extracts / therapeutic use
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Plant Leaves
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Rats
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Rats, Wistar
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Vasoconstriction / drug effects*
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Vasoconstrictor Agents / administration & dosage
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Vasoconstrictor Agents / chemistry
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Vasoconstrictor Agents / pharmacology*
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Vasoconstrictor Agents / therapeutic use
Substances
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Benzyl Compounds
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Glucosides
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Plant Extracts
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Vasoconstrictor Agents