Abstract
As with all viruses, the severe acute respiratory syndrome coronavirus (SARS-CoV) utilizes specific host cell factors during its infection cycle. Some of these factors have been identified and are now increasingly scrutinized as targets to intervene with infection. In this brief review, we describe the current understanding of how the SARS-CoV is able to use the cellular machinery for its replication.
Publication types
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Research Support, Non-U.S. Gov't
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Review
MeSH terms
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Humans
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Membrane Glycoproteins / physiology
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Models, Biological
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RNA, Viral / biosynthesis
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Severe Acute Respiratory Syndrome / etiology*
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Severe Acute Respiratory Syndrome / physiopathology
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Severe Acute Respiratory Syndrome / virology
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Severe acute respiratory syndrome-related coronavirus / growth & development
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Severe acute respiratory syndrome-related coronavirus / pathogenicity
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Severe acute respiratory syndrome-related coronavirus / physiology
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Spike Glycoprotein, Coronavirus
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Viral Envelope Proteins / physiology
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Virus Assembly
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Virus Replication / physiology
Substances
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Membrane Glycoproteins
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RNA, Viral
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Spike Glycoprotein, Coronavirus
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Viral Envelope Proteins