Does ASPA gene mutation in Canavan disease alter oligodendrocyte development? A tissue culture study of ASPA KO mice brain

Adv Exp Med Biol. 2006:576:175-82; discussion 361-3. doi: 10.1007/0-387-30172-0_12.

Authors

Shalini Kumar¹, Rasika Sowmyalakshmi, Sarah L Daniels, Ruth Chang, Sankar Surendran, Reuben Matalon, Jean de Vellis

Affiliation

¹ Mental Retardation Research Center, Department of Neurobiology and Psychiatry, Brain Research Institute, David Geffen School of Medicine, University of California, Los Angeles, USA.

PMID: 16802712
DOI: 10.1007/0-387-30172-0_12

No abstract available

MeSH terms

Amidohydrolases / genetics*
Amidohydrolases / metabolism
Animals
Animals, Newborn
Canavan Disease* / enzymology
Canavan Disease* / genetics
Cells, Cultured
Humans
Mice
Mice, Knockout
Mutation*
Neurons / cytology
Neurons / metabolism
Oligodendroglia / cytology
Oligodendroglia / physiology*
Rats

Substances

Amidohydrolases
aspartoacylase