Maturity-onset diabetes of the young with necrobiosis lipoidica and granuloma annulare

Pediatr Dermatol. 2006 May-Jun;23(3):247-50. doi: 10.1111/j.1525-1470.2006.00227.x.

Abstract

We describe a 12-year-old white girl with granuloma annulare localized to both ankles since she was five, necrobiosis lipoidica in the left pretibial region since she was ten, and a recent history of weakness, migraine, and weight loss. After initial evaluation, high fasting blood glucose levels and high hemoglobin A1c were found. The family history for non-insulin-dependent diabetes was suggestive of maturity-onset diabetes of the young. Coexistence of necrobiosis lipoidica and granuloma annulare, together with a family history of non-insulin-dependent diabetes, the age of onset, and the absence of ketosis, are specific features making possible, a clinical diagnosis. Genetic confirmation may not be so easily accessible or necessary.

Publication types

  • Case Reports

MeSH terms

  • Child
  • Diabetes Mellitus, Type 2 / complications*
  • Diabetes Mellitus, Type 2 / diagnosis*
  • Diabetes Mellitus, Type 2 / genetics
  • Female
  • Granuloma Annulare / etiology*
  • Humans
  • Necrobiosis Lipoidica / etiology*