[A case of pneumonitis suspected to be induced by Oseltamivir]

Nihon Kokyuki Gakkai Zasshi. 2006 May;44(5):410-4.
[Article in Japanese]

Abstract

A 33-year-old man had a high fever and was given Cefcapene and Oseltamivir without a definite diagnosis of influenza. Three days later an abnormal chest shadow was pointed out. Chest CT revealed ground-glass opacities and air-space consolidation in bilateral lung fields. Although he was given antibiotics, lung infiltrates increased and his symptoms worsened. Therefore, he was transferred to our hospital. Corticosteroid pulse-therapy resulted in prompt improvement of chest infiltrates and his symptoms. The drug-induced lymphocyte stimulating test results indicated 170% of oseltamivir and 150% of cefcapene. Considering the clinical course and laboratory data, this was probably drug-induced lung injury caused by oseltamivir.

Publication types

  • Case Reports

MeSH terms

  • Acetamides / adverse effects*
  • Adult
  • Antiviral Agents / adverse effects*
  • Diagnosis, Differential
  • Humans
  • Male
  • Oseltamivir
  • Pneumonia / chemically induced*
  • Pneumonia / diagnostic imaging
  • Radiography
  • Severe Acute Respiratory Syndrome / diagnosis

Substances

  • Acetamides
  • Antiviral Agents
  • Oseltamivir