Direct preparation of copper organometallics bearing an aldehyde function via an iodine-copper exchange

Chem Commun (Camb). 2006 Jun 21:(23):2486-8. doi: 10.1039/b604259g. Epub 2006 May 3.

Abstract

The iodine-copper exchange reaction allows the direct preparation of various aryl, heteroaryl and alkenyl cuprates bearing a formyl group, thus allowing a direct synthesis of polyfunctional aldehydes without the need of protecting groups or an additional oxidation step.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Aldehydes / chemical synthesis*
  • Aldehydes / chemistry
  • Copper / chemistry*
  • Iodine / chemistry*
  • Molecular Structure
  • Organometallic Compounds / chemical synthesis*
  • Organometallic Compounds / chemistry
  • Stereoisomerism

Substances

  • Aldehydes
  • Organometallic Compounds
  • Copper
  • Iodine