Abstract
Two new gamma-pyranone derivatives and a new triterpene, together with eight known compounds, were isolated from the aerial parts of Erigeron annuus. Their structures were elucidated by spectroscopic methods. Besides, the anti-tumor activities of the gamma-pyranone derivatives to human hepatoma (SMMC-7721), human embryo liver (L-02) and human leukemia (HL-60) cells were evaluated.
Publication types
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Research Support, Non-U.S. Gov't
MeSH terms
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Antineoplastic Agents, Phytogenic / chemistry
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Antineoplastic Agents, Phytogenic / pharmacology*
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Asteraceae / chemistry*
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Camptothecin / analogs & derivatives
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Camptothecin / pharmacology
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Carcinoma, Hepatocellular / drug therapy
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Cell Line, Tumor
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Erigeron / chemistry*
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Flavanones / chemistry
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Flavanones / pharmacology*
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HL-60 Cells
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Humans
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Magnetic Resonance Spectroscopy
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Pyrones / chemistry
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Pyrones / pharmacology*
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Tumor Cells, Cultured
Substances
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Antineoplastic Agents, Phytogenic
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Flavanones
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Pyrones
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10-hydroxycamptothecin
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Camptothecin