Lung injury from "liquid ecstasy": a role for coagulation activation?

Pediatr Emerg Care. 2006 May;22(5):358-60. doi: 10.1097/01.pec.0000215369.64106.9c.

Abstract

We describe our second clinical observation of pulmonary injury after a "liquid ecstasy" ingestion/inhalation by a 3-year-old girl. Apart from the deep coma state, a markedly asymmetric pulmonary compromise was recorded. A transient coagulation activation was detected, possibly triggered off by the toxic effect on the lung alveolar-capillary membrane.

Publication types

  • Case Reports

MeSH terms

  • Administration, Oral
  • Anticoagulants / therapeutic use
  • Antithrombin III / therapeutic use
  • Blood Coagulation Disorders / blood
  • Blood Coagulation Disorders / chemically induced
  • Blood Coagulation Disorders / drug therapy
  • Child, Preschool
  • Female
  • Hallucinogens / poisoning*
  • Humans
  • Inhalation Exposure
  • N-Methyl-3,4-methylenedioxyamphetamine / poisoning*
  • Pulmonary Edema / blood*
  • Pulmonary Edema / chemically induced*
  • Pulmonary Edema / diagnosis
  • Pulmonary Edema / therapy
  • Serine Proteinase Inhibitors / therapeutic use
  • Treatment Outcome

Substances

  • Anticoagulants
  • Hallucinogens
  • Serine Proteinase Inhibitors
  • Antithrombin III
  • N-Methyl-3,4-methylenedioxyamphetamine