Regression of aortic aneurysms through pharmacologic therapy?

N Engl J Med. 2006 May 11;354(19):2067-8. doi: 10.1056/NEJMcibr060899.
No abstract available

MeSH terms

  • Animals
  • Anthracenes / pharmacology
  • Anthracenes / therapeutic use*
  • Aortic Aneurysm, Abdominal / drug therapy
  • Aortic Aneurysm, Abdominal / metabolism
  • Aortic Aneurysm, Abdominal / prevention & control*
  • Aortic Rupture / prevention & control
  • Disease Models, Animal
  • Extracellular Matrix / drug effects
  • Extracellular Matrix / genetics
  • Extracellular Matrix / metabolism*
  • Gene Expression Profiling
  • Humans
  • MAP Kinase Kinase 4 / antagonists & inhibitors*
  • MAP Kinase Kinase 4 / metabolism
  • Matrix Metalloproteinase 9 / metabolism
  • Mice

Substances

  • Anthracenes
  • pyrazolanthrone
  • MAP Kinase Kinase 4
  • Matrix Metalloproteinase 9