No association between GB virus C infection and disease progression in HIV-2-infected patients from the French ANRS HIV-2 cohort

AIDS. 2006 Apr 24;20(7):1076-9. doi: 10.1097/01.aids.0000222086.29164.6e.

Abstract

Out of 183 HIV-2-infected patients tested in the ANRS CO8 HIV-2 cohort, 69 were exposed to GB virus C (GBV-C), yielding a prevalence of 38% (95% CI 30.7, 45.2). There was no significant difference between the CD4 cell count and HIV-2-RNA plasma viral load in patients exposed and not exposed to GBV-C. After adjusting for age and CD4 cell count, co-infection with GBV-C was not associated with clinical progression (hazard ratio 0.78; 95% CI 0.24-2.56, 16 clinical events).

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adult
  • Antibodies, Viral / analysis
  • CD4 Lymphocyte Count
  • Cohort Studies
  • Disease Progression
  • Female
  • Flaviviridae Infections / complications*
  • Flaviviridae Infections / epidemiology
  • Flaviviridae Infections / virology
  • France / epidemiology
  • GB virus C*
  • HIV Infections / complications*
  • HIV Infections / epidemiology
  • HIV Infections / virology
  • HIV-1
  • HIV-2*
  • Humans
  • Male
  • Prevalence
  • RNA, Viral / analysis
  • Viral Load

Substances

  • Antibodies, Viral
  • RNA, Viral