Afzeliixanthones A and B, two new prenylated xanthones from Garcinia afzelii ENGL. (Guttiferae)

Chem Pharm Bull (Tokyo). 2006 Apr;54(4):448-51. doi: 10.1248/cpb.54.448.

Abstract

Two new prenylated xanthones, afzeliixanthones A (1) and B (2), together with three known xanthones (3-5) and two phytosterols, beta-sitosterol and stigmasterol, were isolated from the CH2Cl2/MeOH (1:1) extract of the stem bark of Garcinia afzelii ENGL. collected in the South West Province of Cameroon. Structures were mainly established using one and two-dimensional NMR and mass spectroscopies. The antioxidant activities of the crude extracts as well as the new compounds (1) and (2) were evaluated.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Antioxidants / pharmacology*
  • Garcinia / chemistry*
  • Magnetic Resonance Spectroscopy
  • Molecular Structure
  • Plant Bark / chemistry
  • Plant Extracts / chemistry
  • Plants, Medicinal / chemistry
  • Sitosterols / chemistry
  • Sitosterols / isolation & purification*
  • Sitosterols / pharmacology
  • Stigmasterol / chemistry
  • Stigmasterol / isolation & purification*
  • Stigmasterol / pharmacology
  • Xanthones / chemistry
  • Xanthones / isolation & purification*
  • Xanthones / pharmacology

Substances

  • Antioxidants
  • Plant Extracts
  • Sitosterols
  • Xanthones
  • afzeliixanthone A
  • afzeliixanthone B
  • gamma-sitosterol
  • Stigmasterol