Structural development of free or coordinated 4'-(4-pyridyl)-2,2':6',2''-terpyridine ligands through N-alkylation: new strategies for metallamacrocycle formation

Chemistry. 2006 Jun 2;12(17):4600-10. doi: 10.1002/chem.200600069.

Abstract

A series of N-alkylated derivatives of [Ru(pytpy)(2)]2+ (pytpy=4'-(4-pyridyl)-2,2':6',2''-terpyridine) has been synthesised and characterised. These include both model and functionalised complexes that complement previously reported iron(II) analogues. Reaction of [Ru(pytpy)(2)]2+ with bis[4-(bromomethyl)phenyl]methane leads to the formation of a [2+2] ruthenamacrocycle. Related ferramacrocycles could not be accessed by this route, and instead were prepared in two steps by first reacting bis[4-(bromomethyl)phenyl]methane or 4,4'-bis(bromomethyl)biphenyl with two equivalents of pytpy, and then treating the resulting bis(N-alkylated) product with iron(II) salts.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Alkylation
  • Ligands
  • Models, Molecular
  • Molecular Conformation
  • Molecular Structure
  • Organometallic Compounds / chemistry*
  • Pyridines / chemistry*
  • Ruthenium / chemistry*

Substances

  • (2,2'-6',2'')-terpyridine
  • Ligands
  • Organometallic Compounds
  • Pyridines
  • Ruthenium