Could the long-term persistence of low serum calcium levels and high serum parathyroid hormone levels during bisphosphonate treatment predispose metastatic breast cancer patients to undergo osteonecrosis of the jaw?

MeSH terms

• Adult
• Aged
• Aged, 80 and over
• Bone Density Conservation Agents / adverse effects*
• Bone Density Conservation Agents / therapeutic use
• Bone Neoplasms / drug therapy*
• Bone Neoplasms / secondary
• Breast Neoplasms / pathology*
• Calcium / blood
• Calcium / toxicity*
• Diphosphonates / adverse effects*
• Diphosphonates / therapeutic use
• Female
• Humans
• Jaw Diseases / chemically induced*
• Middle Aged
• Osteonecrosis / chemically induced*
• Parathyroid Hormone / blood
• Parathyroid Hormone / toxicity*