Variability of aortic valve calcification measurement with multislice spiral computed tomography

Invest Radiol. 2006 Apr;41(4):370-3. doi: 10.1097/01.rli.0000197979.44181.92.

Abstract

Objectives: We sought to assess the variability of aortic valve calcifications (AVCs) regarding the reconstruction window at different heart phases using multislice-spiral computed tomography.

Materials and methods: A total of 46 patients (26 men; mean age. 65 years) underwent AVC scoring with multislice-spiral computed tomography (12 x 0.75 mm, 120 kV, 133 mAseff). Image reconstruction was performed every 10% of the RR-interval (0-90%). AVC was quantified using Agatston score, calcium volume, and calcium mass. Images were assessed for least motion artifacts. Coefficients of variation and Wilcoxon test were calculated.

Results: AVC scores are lowest at 60% and highest at 0% of the RR-interval (P < 0.001). Mean coefficients of variation were 36.2% (Agatston score), 38.7% (calcium volume), and 32.9% (calcium mass). At 60% (50-70%). minimal motion artifacts and the lowest variability of the scores were found.

Conclusions: AVC scores show large variability depending on the point of image reconstruction. Diastolic image reconstruction at 60% of the RR-interval is recommended.

MeSH terms

  • Adult
  • Aged
  • Aged, 80 and over
  • Aortic Valve / diagnostic imaging*
  • Aortic Valve Stenosis / diagnostic imaging*
  • Calcinosis / diagnostic imaging*
  • Diastole
  • Female
  • Heart Rate / physiology*
  • Humans
  • Image Processing, Computer-Assisted*
  • Male
  • Middle Aged
  • Pilot Projects
  • Radiation Dosage
  • Severity of Illness Index
  • Tomography, Spiral Computed / methods*