Abstract
We report 4 cases of community-acquired infections due to Staphylococcus aureus producing Panton-Valentin leukocidin (SA-PVL) with uncommon multivisceral localizations. These cases highlight the need to screen for PVL in patients with serious staphylococcal infections. All patients were cured. Two of them received intravenous immunoglobulins in addition to antibiotics.
MeSH terms
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Adult
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Anti-Bacterial Agents / therapeutic use
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Bacterial Toxins / biosynthesis*
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Bacterial Toxins / genetics
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Community-Acquired Infections / epidemiology
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Community-Acquired Infections / microbiology
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Community-Acquired Infections / pathology
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Exotoxins / biosynthesis*
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Exotoxins / genetics
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Female
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France / epidemiology
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Humans
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Immunoglobulins, Intravenous / therapeutic use
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Leukocidins
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Male
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Staphylococcal Infections / epidemiology*
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Staphylococcal Infections / microbiology
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Staphylococcal Infections / pathology
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Staphylococcus aureus / isolation & purification
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Staphylococcus aureus / pathogenicity
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Viscera / microbiology
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Viscera / pathology
Substances
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Anti-Bacterial Agents
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Bacterial Toxins
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Exotoxins
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Immunoglobulins, Intravenous
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Leukocidins
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Panton-Valentine leukocidin