Adenosine and dialysis hypotension

Kidney Int. 2006 Mar;69(5):789-91. doi: 10.1038/sj.ki.5000232.

Abstract

In this issue, Imai et al. report the results of a double-blind placebo-controlled study on the effect of an adenosine A1 receptor antagonist, FK352, on the incidence of dialysis hypotension in hypotension-prone patients. This Commentary discusses the use of selective adenosine A1 receptor antagonists for the prevention of dialysis hypotension from the perspective of the potential role of adenosine in its pathogenesis.

Publication types

  • Comment

MeSH terms

  • Adenosine / physiology*
  • Adenosine A1 Receptor Antagonists
  • Humans
  • Hypotension / etiology*
  • Hypotension / physiopathology*
  • Hypotension / prevention & control
  • Models, Cardiovascular
  • Pyrazoles / therapeutic use
  • Pyridines / therapeutic use
  • Renal Dialysis / adverse effects*

Substances

  • Adenosine A1 Receptor Antagonists
  • FK 352
  • Pyrazoles
  • Pyridines
  • Adenosine