In vitro antioxidant activity of acetylated and benzoylated derivatives of polysaccharide extracted from Ulva pertusa (Chlorophyta)

Huimin Qi; Quanbin Zhang; Tingting Zhao; Rugui Hu; Kun Zhang; Zhien Li

doi:10.1016/j.bmcl.2006.01.076

In vitro antioxidant activity of acetylated and benzoylated derivatives of polysaccharide extracted from Ulva pertusa (Chlorophyta)

Bioorg Med Chem Lett. 2006 May 1;16(9):2441-5. doi: 10.1016/j.bmcl.2006.01.076. Epub 2006 Feb 14.

Authors

Huimin Qi¹, Quanbin Zhang, Tingting Zhao, Rugui Hu, Kun Zhang, Zhien Li

Affiliation

¹ Institute of Oceanology, Chinese Academy of Sciences, Qingdao 266071, PR China. qihuimin@ms.qdio.ac.cn

PMID: 16481163
DOI: 10.1016/j.bmcl.2006.01.076

Abstract

The antioxidant activity of natural ulvan and its derivatives (acetylated and benzoylated ulvans) in vitro was determined, including scavenging activity against superoxide and hydroxyl radicals, reducing power, and chelating ability. Obvious differences in antioxidant activity between natural ulvan and its derivatives were observed, moreover, the antioxidant activity of acetylated and benzoylated ulvans was stronger than that of natural ulvan.

Publication types

Comparative Study
Research Support, Non-U.S. Gov't

MeSH terms

Acetylation
Antioxidants / chemical synthesis
Antioxidants / chemistry
Antioxidants / pharmacology*
Carbohydrate Conformation
Carbohydrate Sequence
Dose-Response Relationship, Drug
Free Radical Scavengers / chemical synthesis
Free Radical Scavengers / chemistry
Free Radical Scavengers / pharmacology*
Hydroxyl Radical / antagonists & inhibitors
In Vitro Techniques
Molecular Sequence Data
Polysaccharides / chemical synthesis
Polysaccharides / chemistry
Polysaccharides / pharmacology*
Superoxides / antagonists & inhibitors
Ulva / chemistry*

Substances

Antioxidants
Free Radical Scavengers
Polysaccharides
Superoxides
Hydroxyl Radical