Vascular and Alzheimer-type pathology in an autopsy study of African-Americans

Neurology. 2006 Feb 14;66(3):433-5. doi: 10.1212/01.wnl.0000196472.93744.57.

Abstract

The authors studied 13 autopsy brains from a larger cohort of 270 African-Americans with a clinical diagnosis of Alzheimer disease (AD), vascular dementia (VaD), or stroke without dementia. Two subjects exhibited changes of pure VaD, 5 had pure AD, and 6 showed a mixture of AD pathology and strokes. Overall, there was good agreement between the pathologic diagnoses and the clinical diagnoses.

Publication types

  • Research Support, N.I.H., Extramural

MeSH terms

  • Aged
  • Aged, 80 and over
  • Alzheimer Disease / ethnology
  • Alzheimer Disease / pathology*
  • Autopsy*
  • Black or African American*
  • Brain / pathology*
  • Cerebral Infarction / ethnology
  • Cerebral Infarction / pathology*
  • Dementia, Vascular / ethnology
  • Dementia, Vascular / pathology*
  • Female
  • Humans
  • Male
  • Single-Blind Method