Abstract
The genome of human cytomegalovirus (HCMV) contains three genes with homology to cellular G protein-coupled receptors (GCRs). Evidence is presented here that all three HCMV GCR genes are transcribed during infection, that they are transcribed as two sets of 3'-coterminal mRNAs, and that their transcription is restricted to the late phase of infection.
Publication types
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Comparative Study
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Research Support, U.S. Gov't, P.H.S.
MeSH terms
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Base Sequence
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Cells, Cultured
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Cytomegalovirus / genetics*
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GTP-Binding Proteins / genetics
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Gene Expression
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Genes, Viral*
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Humans
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In Vitro Techniques
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Molecular Sequence Data
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Oligonucleotides / chemistry
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RNA, Messenger / genetics
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RNA, Viral / genetics
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Receptors, Cell Surface / genetics
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Sequence Homology, Nucleic Acid
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Transcription, Genetic
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Viral Structural Proteins / genetics*
Substances
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Oligonucleotides
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RNA, Messenger
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RNA, Viral
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Receptors, Cell Surface
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Viral Structural Proteins
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GTP-Binding Proteins