Abstract
Exposure of Escherichia coli to nitric oxide (NO) or nitrosating agents causes significant changes in patterns of gene expression. Three recent studies have used microarrays to analyse the response of the E. coli transcriptome to NO and nitrosative stress. Drawing on the array data, I review our current understanding of the E. coli regulatory systems that are involved.
Publication types
-
Research Support, U.S. Gov't, Non-P.H.S.
-
Review
MeSH terms
-
Bacterial Proteins / genetics
-
Bacterial Proteins / metabolism
-
DNA-Binding Proteins / genetics
-
DNA-Binding Proteins / metabolism
-
Escherichia coli / metabolism*
-
Escherichia coli Proteins / genetics
-
Escherichia coli Proteins / metabolism
-
Iron-Sulfur Proteins / genetics
-
Iron-Sulfur Proteins / metabolism
-
Nitric Oxide / metabolism*
-
Oligonucleotide Array Sequence Analysis
-
Repressor Proteins / genetics
-
Repressor Proteins / metabolism
-
Trans-Activators / genetics
-
Trans-Activators / metabolism
-
Transcription Factors / genetics
-
Transcription Factors / metabolism
Substances
-
Bacterial Proteins
-
DNA-Binding Proteins
-
Escherichia coli Proteins
-
FNR protein, E coli
-
Iron-Sulfur Proteins
-
MetR protein, Bacteria
-
NorR protein, E coli
-
Repressor Proteins
-
Trans-Activators
-
Transcription Factors
-
ferric uptake regulating proteins, bacterial
-
oxyR protein, E coli
-
SoxR protein, Bacteria
-
SoxS protein, E coli
-
Nitric Oxide