Abstract
The development of hemorrhagic cystitis (HC) and urinary excretion of polyoma BK virus (BKV) and adenovirus (ADV) was investigated by polymerase chain reaction in 20 children undergoing allogeneic stem cell transplantation. Five children developed HC, and all of them excreted BKV; however, only 1 excreted ADV, suggesting that BKV is more significant cause of HC than ADV in children undergoing stem cell transplantation.
MeSH terms
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Adenoviridae / genetics
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Adenoviridae / isolation & purification*
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Adenoviridae Infections / diagnosis*
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Adenoviridae Infections / virology
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Adolescent
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BK Virus / genetics
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BK Virus / isolation & purification*
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Child
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Child, Preschool
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Cystitis / virology*
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Female
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Hematologic Neoplasms / complications
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Hematopoietic Stem Cell Transplantation / adverse effects*
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Humans
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Infant
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Male
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Polymerase Chain Reaction
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Polyomavirus Infections / diagnosis*
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Polyomavirus Infections / virology
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Transplantation, Homologous / adverse effects
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Tumor Virus Infections / diagnosis
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Tumor Virus Infections / virology
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Urine / virology