Prevalence and evolution of methicillin-resistant Staphylococcus aureus in Spanish hospitals between 1996 and 2002

J Clin Microbiol. 2006 Jan;44(1):266-70. doi: 10.1128/JCM.44.1.266-270.2006.

Abstract

Pulsed-field gel electrophoretic analysis of 2,144 methicillin-resistant Staphylococcus aureus (MRSA) strains isolated from patients in Spanish hospitals over a 7-year period revealed 17 predominant profiles. Typing showed the replacement of Iberian clone E1 (ST247-MRSA-I) by two prevalent clones, E7 and E8, that are closely related to each other and have the same genetic background as ST125-MRSA-IV.

MeSH terms

  • Biological Evolution
  • Electrophoresis, Gel, Pulsed-Field / methods
  • Evolution, Molecular*
  • Genes, Bacterial / genetics
  • Hospitals
  • Methicillin / pharmacology
  • Methicillin Resistance / genetics*
  • Prevalence
  • Spain
  • Staphylococcal Infections / epidemiology*
  • Staphylococcal Infections / microbiology
  • Staphylococcus aureus / classification*
  • Staphylococcus aureus / drug effects
  • Staphylococcus aureus / genetics

Substances

  • Methicillin