Breaking up (amyloid) is hard to do

PLoS Med. 2005 Dec;2(12):e417. doi: 10.1371/journal.pmed.0020417. Epub 2005 Dec 27.

Abstract

Gandy and Heppner discuss the implications of a new animal study on our understanding of the pathogenesis and treatment of Alzheimer disease.

Publication types

  • Comment
  • Research Support, N.I.H., Extramural

MeSH terms

  • Aged
  • Alzheimer Disease / physiopathology*
  • Alzheimer Disease / prevention & control
  • Amyloid beta-Peptides / metabolism*
  • Amyloid beta-Peptides / physiology
  • Amyloid beta-Protein Precursor / biosynthesis
  • Animals
  • Disease Models, Animal
  • Humans
  • Mice
  • Mice, Transgenic
  • Plaque, Amyloid*

Substances

  • Amyloid beta-Peptides
  • Amyloid beta-Protein Precursor