Assessment of the solid-state gamma camera to depict axillary sentinel lymph nodes in breast cancer patients

Ann Nucl Med. 2005 Oct;19(7):627-31. doi: 10.1007/BF02985058.

Abstract

Purpose: The solid-state gamma camera is now commercially available offering the advantages of a compact and portable system, currently used mainly in the cardiac region. We evaluate the ability of the solid-state gamma camera to depict axillary sentinel lymph nodes (SLNs) in breast cancer patients.

Materials and methods: Preoperative SLN lymphoscintigraphy (LSG) was performed in 19 patients with breast cancer using the solid-state gamma camera. Immediately thereafter, we performed a second LSG using a single detector Anger-type gamma camera, and compared the findings from the two cameras.

Results: Concordant results were obtained in 12 (63%) patients with both cameras. In 4 (21%) patients, axillary SLNs were correctly identified only with the solid-state gamma camera. In these patients, the distance between the SLN and the radiopharmaceutical injection site was closer than that of patients who had concordant results (p = 0.001).

Conclusion: We can depict correctly axillary SLNs with the solid-state gamma camera in comparison with the Anger-type gamma camera. This technique would be useful for assessing SLNs in breast cancer patients.

Publication types

  • Clinical Trial

MeSH terms

  • Adult
  • Axilla / diagnostic imaging*
  • Breast Neoplasms / diagnostic imaging*
  • Equipment Failure Analysis
  • Humans
  • Image Enhancement / instrumentation*
  • Image Enhancement / methods
  • Lymph Nodes / diagnostic imaging*
  • Lymph Nodes / pathology*
  • Lymphatic Metastasis
  • Male
  • Middle Aged
  • Radionuclide Imaging / instrumentation*
  • Radionuclide Imaging / methods
  • Reproducibility of Results
  • Semiconductors
  • Sensitivity and Specificity
  • Sentinel Lymph Node Biopsy / methods*