Abstract
Mesoderm and endoderm formation in Xenopus involves the coordinated efforts of maternally and zygotically expressed transcription factors together with growth factor signalling, including members of the TGFbeta and wnt families. In this review we discuss our current state of knowledge of these pathways, and describe in more detail some of the transcription factor-DNA interactions that are involved in mesendoderm formation.
Publication types
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Research Support, Non-U.S. Gov't
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Review
MeSH terms
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Animals
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Body Patterning*
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Endoderm / physiology*
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Gene Expression Regulation, Developmental*
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Mesoderm / physiology*
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Signal Transduction / physiology*
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Transcription Factors / metabolism
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Transcription, Genetic*
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Transforming Growth Factor beta / metabolism
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Xenopus Proteins / metabolism
Substances
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Transcription Factors
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Transforming Growth Factor beta
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Xenopus Proteins