Case-control analyses: Geneopardy!

Genet Epidemiol. 2005:29 Suppl 1:S86-90. doi: 10.1002/gepi.20114.

Abstract

The case-control analyses group focused on a diverse set of questions, including study design, power, and analysis of case-control studies. Papers on study design examined various case-selection strategies, as well as ways to combine information from family- and population-based case-control data. The power of various approaches to case-control analyses was compared in several papers, while two papers chose to apply specific methods to analyzing the data. Two groups examined haplotype-related issues, including resolving un-phased haplotypes and comparing haplotype- and single-nucleotide polymorphism-based methods for analyzing data. Finally, one group examined the optimal number of markers for the genomic control approach to population stratification.

MeSH terms

  • Alcoholism / genetics*
  • Case-Control Studies*
  • Chromosome Mapping / methods*
  • Cytogenetic Analysis / methods*
  • Genetic Predisposition to Disease / genetics
  • Genotype
  • Humans
  • Linkage Disequilibrium / genetics
  • Phenotype
  • Polymorphism, Single Nucleotide / genetics
  • Quantitative Trait Loci / genetics
  • Tandem Repeat Sequences / genetics