Partial seizures triggering infantile spasms in the presence of a basal ganglia glioma

Epileptic Disord. 2005 Dec;7(4):378-82.

Abstract

Infantile spasms associated with brain tumors have been reported. A focal cortical lesion can induce infantile spasms by triggering the brainstem and basal ganglia in this vulnerable age group. We report the case of a female infant with a low-grade glioma in the right basal ganglia, spreading to the cortical area. She presented at the age of five months with left hemiparesis and partial seizures. She developed infantile spasms at the age of 12 months. This is the first video clip report of partial seizures triggering symmetrical spasms in series, secondary to a basal ganglia glioma extending to the cortex. [Published with video sequences].

Publication types

  • Case Reports
  • Review

MeSH terms

  • Anticonvulsants / therapeutic use
  • Antineoplastic Combined Chemotherapy Protocols / therapeutic use
  • Astrocytoma / complications*
  • Astrocytoma / diagnosis
  • Astrocytoma / drug therapy
  • Astrocytoma / physiopathology
  • Cerebral Cortex / pathology
  • Cerebral Cortex / physiopathology
  • Corpus Striatum / pathology*
  • Corpus Striatum / physiopathology
  • Developmental Disabilities / etiology
  • Electroencephalography
  • Epilepsies, Partial / drug therapy
  • Epilepsies, Partial / etiology*
  • Globus Pallidus / pathology*
  • Globus Pallidus / physiopathology
  • Humans
  • Infant
  • Paresis / etiology
  • Spasms, Infantile / drug therapy
  • Spasms, Infantile / etiology*
  • Spasms, Infantile / physiopathology
  • Supratentorial Neoplasms / complications*
  • Supratentorial Neoplasms / diagnosis
  • Supratentorial Neoplasms / drug therapy
  • Supratentorial Neoplasms / physiopathology

Substances

  • Anticonvulsants