Alexia without agraphia following cerebral venous thrombosis associated with protein C and protein S deficiency

Clin Neurol Neurosurg. 2005 Dec;108(1):52-5. doi: 10.1016/j.clineuro.2004.11.005. Epub 2004 Dec 8.

Abstract

A 26-year-old right handed female was admitted to hospital with right homonymous hemianopia associated with alexia without agraphia. Her cranial magnetic resonance imaging and magnetic resonance angiography revealed a left occipital venous infarction due to thrombosis of the left transverse, sigmoid sinuses and the left internal jugulary vein. The underlying conditions were protein C and protein S deficiency associated with the use of oral contraceptives. To our knowledge, alexia without agraphia has never been described due to a venous infarction associated with hereditary thrombophilia in the literature.

Publication types

  • Case Reports

MeSH terms

  • Adult
  • Alexia, Pure / etiology*
  • Female
  • Humans
  • Intracranial Thrombosis / complications*
  • Intracranial Thrombosis / diagnosis
  • Intracranial Thrombosis / therapy
  • Protein C Deficiency / complications*
  • Protein C Deficiency / diagnosis
  • Protein C Deficiency / therapy
  • Protein S Deficiency / complications*
  • Protein S Deficiency / diagnosis
  • Protein S Deficiency / therapy
  • Venous Thrombosis / complications*
  • Venous Thrombosis / diagnosis
  • Venous Thrombosis / therapy