Isolation of measles virus from middle ear fluid of infants with acute otitis media

Hisakazu Yano; Mitsuko Suetake; Hiroko Endo; Reiko Takayanagi; Mika Numata; Kenji Ohyama; Shun Sagai; Naohiro Okitsu; Michiko Okamoto; Hidekazu Nishimura; Toshimitsu Kobayashi

doi:10.1016/j.jinf.2004.09.002

Isolation of measles virus from middle ear fluid of infants with acute otitis media

J Infect. 2005 Nov;51(4):e237-40. doi: 10.1016/j.jinf.2004.09.002.

Authors

Hisakazu Yano¹, Mitsuko Suetake, Hiroko Endo, Reiko Takayanagi, Mika Numata, Kenji Ohyama, Shun Sagai, Naohiro Okitsu, Michiko Okamoto, Hidekazu Nishimura, Toshimitsu Kobayashi

Affiliation

¹ Department of Otolaryngology, Tohoku Rosai Hospital, Aoba-ku, Sendai 981-8563, Japan. yanohisa@tohokuh.rofuku.go.jp

PMID: 16291278
DOI: 10.1016/j.jinf.2004.09.002

Abstract

Measles virus was isolated from the middle ear fluid (MEF) of two infant cases of acute otitis media (AOM) associated with measles. This is the first report on the isolation of measles virus from the MEF in patients with AOM, and possibility of the measles virus as a causative agent of AOM was suggested.

MeSH terms

Acute Disease
Biopsy, Fine-Needle
Ear, Middle / virology*
Female
Humans
Infant
Male
Measles / complications*
Measles / virology
Measles virus / isolation & purification*
Otitis Media / diagnosis
Otitis Media / therapy
Otitis Media / virology*
Otoscopy / methods
Tympanic Membrane / pathology