Abstract
Platelet plays an important role in bleeding and thrombotic diseases. Humanized anti-platelet antibodies have great clinical effects in treatment of ITP and preventing thrombosis. The important role of platelet in bleeding and thrombotic diseases, the present status of development on study of humanized anti-platelet antibody and its application in treatment of bleeding and thrombotic diseases were summarized in this review.
Publication types
-
English Abstract
-
Research Support, Non-U.S. Gov't
-
Review
MeSH terms
-
Animals
-
Antibodies, Monoclonal / biosynthesis
-
Antibodies, Monoclonal / immunology*
-
Antibodies, Monoclonal / therapeutic use
-
Autoantibodies / immunology*
-
Blood Platelets / immunology*
-
Humans
-
Platelet Glycoprotein GPIIb-IIIa Complex / biosynthesis
-
Platelet Glycoprotein GPIIb-IIIa Complex / immunology*
-
Platelet Glycoprotein GPIb-IX Complex / immunology
Substances
-
Antibodies, Monoclonal
-
Autoantibodies
-
Platelet Glycoprotein GPIIb-IIIa Complex
-
Platelet Glycoprotein GPIb-IX Complex