The Toll-like receptor 4 Asp299Gly and Thr399Ile polymorphisms influence the late inflammatory response in human endotoxemia

Clin Chem. 2005 Nov;51(11):2178-80. doi: 10.1373/clinchem.2005.051649.
No abstract available

MeSH terms

  • Amino Acid Substitution
  • Biomarkers
  • C-Reactive Protein / analysis
  • Endotoxemia / metabolism
  • Endotoxemia / physiopathology*
  • Escherichia coli
  • Fibrin Fibrinogen Degradation Products / analysis
  • Humans
  • Inflammation / metabolism
  • Interleukin-1 / blood
  • Interleukin-6 / blood
  • Lipopolysaccharides / pharmacology
  • Male
  • Mutation
  • Polymorphism, Genetic
  • Toll-Like Receptor 4 / genetics*
  • Tumor Necrosis Factor-alpha / analysis

Substances

  • Biomarkers
  • Fibrin Fibrinogen Degradation Products
  • Interleukin-1
  • Interleukin-6
  • Lipopolysaccharides
  • Toll-Like Receptor 4
  • Tumor Necrosis Factor-alpha
  • fibrin fragment D
  • C-Reactive Protein