Progress in clinical neurosciences: a forum on the early management of Parkinson's disease

Can J Neurol Sci. 2005 Aug;32(3):277-86. doi: 10.1017/s0317167100004145.

Abstract

There are numerous concerns related to treatment choices involving early dopaminergic therapy in Parkinson's disease. These include the effect on the underlying progression of the neurodegenerative process as well as the development of motor complications such as fluctuations and dyskinesias. A number of recent basic and clinical studies have provided new insights but have also added confusion and controversy. This report summarizes presentations and discussion dealing with these issues from a one-day symposium involving Canadian Movement Disorders neurologists.

Publication types

  • Research Support, Non-U.S. Gov't
  • Review

MeSH terms

  • Antiparkinson Agents / therapeutic use
  • Dopamine Agonists / therapeutic use
  • Humans
  • Levodopa / therapeutic use
  • Magnetic Resonance Imaging
  • Movement Disorders / etiology
  • Movement Disorders / therapy
  • Parkinson Disease / drug therapy
  • Parkinson Disease / pathology
  • Parkinson Disease / therapy*

Substances

  • Antiparkinson Agents
  • Dopamine Agonists
  • Levodopa