Small intestinal submucosa intracardiac patch: an experimental study

Surg Innov. 2005 Sep;12(3):227-31. doi: 10.1177/155335060501200307.

Abstract

In this experimental study, small intestinal submucosa was implanted as an atrial prosthesis in calves. Echocardiography and histology showed this to be an impermeable prosthesis that develops a neointimal nonthrombogenic surface making it safe for repair of defects in a low-pressure system. Further study with small intestinal submucosa in an intracardiac position is warranted.

Publication types

  • Comparative Study

MeSH terms

  • Animals
  • Biopsy, Needle
  • Cardiac Surgical Procedures / methods*
  • Cattle
  • Disease Models, Animal
  • Graft Rejection
  • Graft Survival
  • Immunohistochemistry
  • Intestinal Mucosa / transplantation*
  • Intestine, Small
  • Male
  • Mitral Valve / pathology*
  • Mitral Valve / surgery*
  • Risk Assessment
  • Sensitivity and Specificity
  • Surgical Flaps