Solution structure of human dihydrofolate reductase in its complex with trimethoprim and NADPH

J Biomol NMR. 2005 Sep;33(1):69-72. doi: 10.1007/s10858-005-1475-z.
No abstract available

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Binding Sites
  • Crystallization
  • Crystallography, X-Ray
  • Folic Acid Antagonists / chemistry*
  • Humans
  • Models, Molecular
  • NADP / chemistry*
  • Nuclear Magnetic Resonance, Biomolecular
  • Protein Conformation
  • Tetrahydrofolate Dehydrogenase / chemistry*
  • Trimethoprim / chemistry*

Substances

  • Folic Acid Antagonists
  • NADP
  • Trimethoprim
  • Tetrahydrofolate Dehydrogenase

Associated data

  • PDB/1YHO