[Tuberculosis due to multidrug resistant Mycobacterium tuberculosis Beijing genotype identified by DNA fingerprinting: the first case identified in Hungary]

Orv Hetil. 2005 Aug 28;146(35):1833-7.
[Article in Hungarian]

Abstract

In a 28 years old Mongolian woman in whom pulmonary tuberculosis was diagnosed a poly- and multidrug (isoniazid, rifampicin, pyrazinamide, ethambutol, streptomycin) resistant Mycobacterium tuberculosis was isolated from sputum in 2002. Since the patient was from a country with high tuberculosis incidence it was conceivable that she had been infected by a strain with primary resistance in Mongolia. In order to confirm the origin of the strain an IS6110-based DNA fingerprint test was performed on the isolate. The assay revealed that the isolated M. tuberculosis strain belonged to the so-called Beijing family which was never detected in Hungary before.

Publication types

  • Case Reports

MeSH terms

  • Adult
  • Antitubercular Agents / pharmacology
  • DNA Fingerprinting*
  • Drug Resistance, Bacterial
  • Female
  • Genotype
  • Humans
  • Hungary
  • Mongolia
  • Mycobacterium tuberculosis* / classification
  • Mycobacterium tuberculosis* / isolation & purification
  • Radiography
  • Tuberculosis, Multidrug-Resistant / diagnosis*
  • Tuberculosis, Multidrug-Resistant / diagnostic imaging
  • Tuberculosis, Pulmonary / diagnosis*
  • Tuberculosis, Pulmonary / diagnostic imaging

Substances

  • Antitubercular Agents