Valproate and HDAC inhibition: a new epigenetic strategy to mitigate phenotypic severity in ALS?

Amyotroph Lateral Scler Other Motor Neuron Disord. 2005 Sep;6(3):185-6. doi: 10.1080/14660820510033614.

Authors

L Tremolizzo¹, V Rodriguez-Menendez, G Sala, J C Di Francesco, C Ferrarese

Affiliation

¹ Department of Neuroscience, University of Milano-Bicocca, Monza, Italy.

PMID: 16183561
DOI: 10.1080/14660820510033614

No abstract available

MeSH terms

Amyotrophic Lateral Sclerosis / drug therapy*
Amyotrophic Lateral Sclerosis / enzymology
Histone Deacetylase Inhibitors*
Humans
Phenotype
Valproic Acid / therapeutic use*

Substances

Histone Deacetylase Inhibitors
Valproic Acid