Diagnostic utility of new immunoassays for the cardiac markers cTnI, myoglobin and CK-MB mass

Clin Biochem. 2005 Nov;38(11):1027-30. doi: 10.1016/j.clinbiochem.2005.07.011. Epub 2005 Aug 24.

Abstract

Objectives: We investigated the diagnostic value of a new system, the Innotrac Aio! immunoassays for troponin, myoglobin and CK-MB, in 270 samples from patients with ACS, after bypass surgery (CABG) or with stable heart failure in comparison to the respective Roche assays.

Results: The values of the cardiac markers assessed by the respective assays correlated (cTnT/cTnI Rho = 0.94, myoglobin Rho = 0.87, CK-MB Rho = 0.84). If values were dichotomised, we found a high concordance of test positive and negative classified patients by troponins with the respective assays.

Conclusion: There is strong evidence that the Innotrac Aio! system for cTnI measurement can be used reliably.

Publication types

  • Comparative Study
  • Evaluation Study

MeSH terms

  • Acute Disease
  • Biomarkers / blood*
  • Coronary Artery Bypass
  • Coronary Disease / blood*
  • Creatine Kinase, MB Form / analysis*
  • Humans
  • Immunoassay / methods*
  • Myoglobin / analysis*
  • Reagent Kits, Diagnostic
  • Troponin T / analysis*

Substances

  • Biomarkers
  • Myoglobin
  • Reagent Kits, Diagnostic
  • Troponin T
  • Creatine Kinase, MB Form