Prognosis of migraine and tension-type headache: a population-based follow-up study

Neurology. 2005 Aug 23;65(4):580-5. doi: 10.1212/01.wnl.0000172918.74999.8a.

Abstract

Objective: To determine the prognosis of migraine and tension-type headache and to identify prognostic factors.

Methods: Of 740 persons (aged 25 to 64 years) examined in a 1989 Danish cross-sectional headache study, 673 were eligible for follow-up in 2001. All interviews at baseline and at follow-up were conducted by medical doctors and based on the 1988 IHS-criteria.

Results: A total of 549 persons (81.6%) participated in the follow-up study. Of 64 migraineurs at baseline, 42% had experienced remission, 38% had low migraine frequency, and 20% had more than 14 migraine days per year (poor outcome) at follow-up. Poor outcome was associated with high migraine frequency at baseline and age at onset younger than 20 years. Among 146 subjects with frequent episodic tension-type headache and 15 with chronic tension-type headache at baseline, 45% experienced infrequent or no tension-type headache (remission), 39% had frequent episodic tension-type headache, and 16% experienced chronic tension-type headache (poor outcome) at follow-up. Poor outcome was associated with baseline chronic tension-type headache, coexisting migraine, not being married, and sleeping problems.

Conclusions: The prognosis of migraine, frequent episodic tension-type headache, and chronic tension-type headache was favorable.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adult
  • Age of Onset
  • Aged
  • Analgesics / adverse effects
  • Causality
  • Cohort Studies
  • Comorbidity
  • Cross-Sectional Studies
  • Disease Progression
  • Female
  • Follow-Up Studies
  • Headache Disorders / chemically induced
  • Headache Disorders / diagnosis
  • Headache Disorders / epidemiology
  • Humans
  • Male
  • Marital Status / statistics & numerical data
  • Middle Aged
  • Migraine Disorders / diagnosis*
  • Migraine Disorders / epidemiology*
  • Migraine Disorders / physiopathology
  • Prognosis
  • Sleep Wake Disorders / epidemiology
  • Tension-Type Headache / diagnosis*
  • Tension-Type Headache / epidemiology*
  • Tension-Type Headache / physiopathology

Substances

  • Analgesics