Purpose: We assessed the prevalence of Peyronie's disease (PD) in type 2 diabetic patients who were screened for erectile dysfunction (ED).
Materials and methods: A total of 1,133 male diabetic Saudi patients were enrolled in this study. Patients were screened for ED using the International Index for Erectile Function. At the screening time, all patients were also interviewed for sociodemographic data and risk factors for ED and diabetes that included age, obesity, smoking, hypertension, dyslipidemia, ischemic heart disease and psychological disorders. Medical history included diabetes, duration of diabetes and diabetes related complications. The diagnosis of Peyronie's disease was based on a palpable penile plaque or acquired penile curvature.
Results: Mean age +/- SD for the study sample was 53.9 +/- 10.8 years. Of the patients, 8.1% were diagnosed as having PD. Penile plaque and curvature were the most common findings. About 75% of the patients had long duration and progressive course of their complaint. Significant associations between PD and both ED and longer duration ED were detected. There were also significant associations between PD and age, obesity, smoking, duration and number of cigarettes smoked per day. Dyslipidemia, psychological disorders and presence of at least 1 risk factor were significantly associated with PD. There were significant associations between longer duration and poor metabolic control of diabetes and PD.
Conclusions: Peyronie's disease was prevalent among diabetic patients being screened for ED. The study offered a quantitative estimate of the prevalence of PD, and investigated the association of main risk factors and comorbidities of diabetes and ED with PD.