Association between method of delivery and puerperal infectious complications in the perinatal database of Baden-Württemberg 1998-2001

Gynecol Obstet Invest. 2005;60(4):213-7. doi: 10.1159/000087208. Epub 2005 Jul 26.

Abstract

The strongest argument against caesarean delivery relates to maternal complications. Evidence supporting this for elective operations is controversial. The perinatal database 1998-2001 of the German state of Baden-Württemberg was studied to assess the maternal obstetrical risk associated with caesarean delivery with regard to puerperal infectious complications. For statistical analysis the chi2 test, Fisher's exact test, Mantel-Haenszel statistics and relative risks were used to describe the risk of exposure. Surgical delivery was associated with a significantly higher risk of infectious disorders (p < 0.0001). There was a significantly higher risk of septicaemia in the group undergoing caesarean compared to vaginal delivery (p < 0.0001), for pregnancies with and without risk factors of infection, and also for caesarean delivery prior to labour and rupture of membranes (ROM) and singleton gestations (RR 8.56; 95% CI 4.4-16.65, stratum without risks). The rate of wound disorders was found to be significantly increased in the case of surgical delivery (p < 0.0001). After exclusion of pregnancies with risk factors for infectious complications and multi-fetal gestation, a significantly higher risk was also found for caesarean delivery prior to labour and ROM versus vaginal delivery (RR 16.97; 95% CI 14.16-20.34). Caesarean delivery significantly increased the likelihood that a woman would experience fever in puerperium (p < 0.0001), for pregnancies with and without ante- or perinatal risk factors for infectious complications, and also when caesarean delivery prior to labour and ROM and singletons in the cephalic presentation were considered separately (RR 11.03; 95% CI 9.39-12.96; stratum without risks). Considering the obstetrical challenge of how more women can deliver with fewer complications, reducing unnecessary caesarean delivery still seems to be an appropriate approach.

MeSH terms

  • Cesarean Section / adverse effects*
  • Databases, Factual
  • Delivery, Obstetric / adverse effects*
  • Extraembryonic Membranes
  • Female
  • Fever / complications
  • Germany / epidemiology
  • Humans
  • Labor, Obstetric
  • Pregnancy
  • Puerperal Infection* / epidemiology
  • Puerperal Infection* / etiology
  • Risk
  • Sepsis / etiology
  • Surgical Wound Infection / epidemiology