Primary angiosarcoma of the ovary: a case report of Stage I disease

Gynecol Oncol. 2005 Oct;99(1):218-21. doi: 10.1016/j.ygyno.2005.05.044.

Abstract

Background: There are 20 documented cases of primary ovarian angiosarcoma. Most patients present with metastatic disease and respond poorly to chemotherapy. There is little information available to counsel early-staged patients on the need for or efficacy of adjuvant chemotherapy.

Case: We present a case of Stage Ic primary ovarian angiosarcoma treated with 3 cycles of adjuvant MAID chemotherapy. The patient is without evidence of disease 10 months post-operatively.

Conclusion: A review of the literature indicates a potential role for MAID chemotherapy in the treatment of ovarian angiosarcomas. Detection of Stage I disease appears to confer a better prognosis regardless of the utilization of adjuvant chemotherapy.

Publication types

  • Case Reports

MeSH terms

  • Adult
  • Antineoplastic Combined Chemotherapy Protocols / administration & dosage
  • Antineoplastic Combined Chemotherapy Protocols / therapeutic use*
  • Chemotherapy, Adjuvant
  • Dacarbazine / administration & dosage
  • Doxorubicin / administration & dosage
  • Female
  • Hemangiosarcoma / drug therapy*
  • Hemangiosarcoma / pathology
  • Hemangiosarcoma / surgery
  • Humans
  • Ifosfamide / administration & dosage
  • Mesna / administration & dosage
  • Neoplasm Staging
  • Ovarian Neoplasms / drug therapy*
  • Ovarian Neoplasms / pathology
  • Ovarian Neoplasms / surgery

Substances

  • Dacarbazine
  • Doxorubicin
  • Mesna
  • Ifosfamide

Supplementary concepts

  • MAID protocol