Comparison of functional activity in host and graft mesenteric lymphoid tissue of rats receiving syngeneic heterotopic small bowel allografts with portal or systemic drainage

Transplant Proc. 1992 Jun;24(3):1133-4.

Abstract

With the accompanying paper these studies provide further evidence that functionally important lymphoid cell trafficking takes place in mesenteric tissue under the apparent control of factor(s) filtered by hepatic tissue. The role that these regulatory mechanisms have to play on survival of vascular allografts with venous drainage into either the portal or systemic circulation remains to be elucidated.

Publication types

  • Comparative Study
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Animals
  • Cytotoxicity, Immunologic
  • Drainage
  • Interleukin-1 / analysis
  • Interleukin-1 / biosynthesis
  • Interleukin-2 / analysis
  • Interleukin-2 / biosynthesis
  • Interleukin-6 / analysis
  • Interleukin-6 / biosynthesis
  • Intestine, Small / transplantation*
  • Lymph Nodes / immunology*
  • Lymphocyte Activation
  • Lymphokines / biosynthesis*
  • Peyer's Patches / immunology*
  • Portal Vein
  • Rats
  • Rats, Inbred BN
  • Rats, Inbred Lew
  • Transplantation, Heterotopic / immunology
  • Transplantation, Isogeneic / immunology*

Substances

  • Interleukin-1
  • Interleukin-2
  • Interleukin-6
  • Lymphokines