A novel HLA-DRB1*15 allelic sequence isolated from the Han population of Guangdong, China

Int J Immunogenet. 2005 Aug;32(4):221-2. doi: 10.1111/j.1744-313X.2005.00514.x.

Abstract

A novel DRB1*15 allele, DRB1*1516, has been identified in a Guangdong Han individual. Its sequence was confirmed by sequencing of polymerase chain reaction products and clones. This allele differed by one nucleotide from DRB1*150101 at position 220 (G-->A), resulting in an amino acid substitution from Gly to Arg at codon 45.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Alleles*
  • Amino Acid Sequence
  • Asian People / genetics*
  • Base Sequence
  • China / ethnology
  • Exons / genetics
  • HLA-DR Antigens / genetics*
  • HLA-DRB1 Chains
  • Humans
  • Molecular Sequence Data
  • Sequence Alignment

Substances

  • HLA-DR Antigens
  • HLA-DRB1 Chains

Associated data

  • GENBANK/AY714542