[Comparative investigation of the hematologic and immunologic effects of splenectomy and spleen autotransplantation in mice]

Magy Seb. 2005 Apr;58(2):84-8.
[Article in Hungarian]

Abstract

We have analysed the hematological and immunological effects of the Furka's spleen chip method of autotransplantation in Balb/c mice two and eight months after splenectomy and autotransplantation. Our results showed that the autotransplants had positive effect on the partial restoration of the damaged elements of both cellular and humoral immunity appearing after splenectomy. However, these beneficial effects may have some dependence of time and species.

Publication types

  • Comparative Study

MeSH terms

  • Animals
  • B-Lymphocytes / immunology*
  • CD3 Complex / immunology*
  • CD4 Antigens / immunology*
  • CD4-Positive T-Lymphocytes / immunology
  • Female
  • Immunoglobulin M / blood*
  • Mice
  • Mice, Inbred BALB C
  • Monitoring, Immunologic / methods
  • Splenectomy* / adverse effects
  • T-Lymphocytes / immunology*
  • Transplantation, Autologous / adverse effects
  • Transplantation, Autologous / immunology

Substances

  • CD3 Complex
  • CD4 Antigens
  • Immunoglobulin M