Epileptiform EEG abnormalities in children with language regression

Neurology. 2005 Jul 12;65(1):129-31. doi: 10.1212/01.wnl.0000167193.53817.0f.

Abstract

The authors examined the records of 149 children with language regression (LR) who had overnight EEG monitoring. Children with isolated LR had a higher frequency of epileptiform abnormalities (60%) than those with LR in the context of autistic regression (31%, p = 0.002) and also a higher rate of clinical seizures (33% vs 8%, p < 0.001). EEG abnormalities in the LR only group were also more prominent. This suggests two subtypes of language regression.

Publication types

  • Research Support, N.I.H., Extramural
  • Research Support, Non-U.S. Gov't
  • Research Support, U.S. Gov't, P.H.S.

MeSH terms

  • Action Potentials / physiology
  • Age of Onset
  • Autistic Disorder / complications*
  • Autistic Disorder / diagnosis
  • Autistic Disorder / physiopathology*
  • Cerebral Cortex / physiopathology
  • Child, Preschool
  • Disease Progression
  • Electroencephalography
  • Epilepsy / complications*
  • Epilepsy / diagnosis
  • Epilepsy / physiopathology*
  • Female
  • Humans
  • Language Development Disorders / diagnosis
  • Language Development Disorders / etiology*
  • Language Development Disorders / physiopathology*
  • Male
  • Monitoring, Physiologic
  • Polysomnography
  • Predictive Value of Tests
  • Prognosis
  • Regression, Psychology
  • Retrospective Studies
  • Sex Factors