Successful treatment of osteolytic epithelioid hemangioendothelioma with pamidronate

Clin Exp Rheumatol. 2005 May-Jun;23(3):400-1.

Abstract

We describe the case of a 70-year-old man with unicentric grade 1 epitheloid hemangioendothelioma (EH) of the bone that favourably responded to intravenous pamidronate as a single agent. After 6 years of follow-up, the patient was in complete remisssion. We suggest that use of bisphosphonates should be considered in the treatment of osteolytic EH.

Publication types

  • Case Reports

MeSH terms

  • Aged
  • Antineoplastic Agents / therapeutic use*
  • Bone Neoplasms / diagnostic imaging
  • Bone Neoplasms / drug therapy*
  • Bone Neoplasms / pathology
  • Diphosphonates / therapeutic use*
  • Disease-Free Survival
  • Fingers / pathology
  • Hemangioendothelioma / diagnostic imaging
  • Hemangioendothelioma / drug therapy*
  • Hemangioendothelioma / pathology
  • Humans
  • Male
  • Osteolysis / diagnostic imaging
  • Osteolysis / drug therapy*
  • Osteolysis / pathology
  • Pamidronate
  • Radiography
  • Treatment Outcome
  • Wrist / pathology

Substances

  • Antineoplastic Agents
  • Diphosphonates
  • Pamidronate