DMC: novel celecoxib derivatives to rap cancer

Cancer Biol Ther. 2005 May;4(5):583-4. doi: 10.4161/cbt.4.5.1794. Epub 2005 May 10.
No abstract available

Publication types

  • Comment
  • Comparative Study

MeSH terms

  • Animals
  • Antineoplastic Agents / pharmacology*
  • Apoptosis / drug effects
  • Celecoxib
  • Cell Cycle Proteins / analysis
  • Cell Cycle Proteins / metabolism
  • Cell Proliferation / drug effects
  • Cyclin A / metabolism
  • Cyclin B / metabolism
  • Cyclin-Dependent Kinase Inhibitor p27 / metabolism
  • Cyclooxygenase Inhibitors / pharmacology
  • Mice
  • Mice, Nude
  • Mitogen-Activated Protein Kinase 1 / metabolism
  • Mitogen-Activated Protein Kinase 3 / metabolism
  • Neoplasm Transplantation
  • Phosphorylation / drug effects
  • Pyrazoles / pharmacology*
  • Sulfonamides / pharmacology*
  • Transplantation, Heterologous
  • Xenograft Model Antitumor Assays

Substances

  • 2,5-dimethylcelecoxib
  • Antineoplastic Agents
  • Cell Cycle Proteins
  • Cyclin A
  • Cyclin B
  • Cyclooxygenase Inhibitors
  • Pyrazoles
  • Sulfonamides
  • Cyclin-Dependent Kinase Inhibitor p27
  • Mitogen-Activated Protein Kinase 1
  • Mitogen-Activated Protein Kinase 3
  • Celecoxib