Highly sensitive and selective room-temperature phosphorescence determination of thiabendazole by the supramolecular interaction of thiabendazole/beta-cyclodextrin/triton X-100

Analyst. 2005 Jul;130(7):1038-45. doi: 10.1039/b503217b. Epub 2005 Jun 9.

Abstract

A strong and stable room temperature phosphorescence (RTP) signal (lambda(ex)/lambda(em) = 298/481 nm) resulting from a 1:1:1 beta-cyclodextrin (beta-CD)/thiabendazole (TBZ)/triton X-100 (TX-100) supramolecular ternary inclusion complex was induced by KI as a heavy atom perturber. Based on the heavy-atom induced RTP, a new phosphorescence method for TBZ determination was established. The analytical curve of TBZ gave a linear range of 20-820 ng mL(-1) with a detection limit and relative standard deviation of 2.1 ng mL(-1) and 1.9%, respectively. The interference of 46 coexisting substances was studied. Compared with the method using a chemical oxygen scavenger, this method is simpler as deoxygenation of the solution is not required. The detection limit and the heavy-atom concentration of the proposed method were decreased about 8 and 4 times, respectively. The lifetime of the phosphorescence was prolonged 9 times and the pH range was greatly broadened. The proposed method has been successfully applied to the determination of TBZ in tap water, lake water and pineapples.

Publication types

  • Evaluation Study
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Anti-Infective Agents / analysis*
  • Food Contamination / analysis
  • Luminescent Measurements / methods
  • Octoxynol / chemistry
  • Temperature
  • Thiabendazole / analysis*
  • Water Pollutants, Chemical / analysis
  • beta-Cyclodextrins / chemistry

Substances

  • Anti-Infective Agents
  • Water Pollutants, Chemical
  • beta-Cyclodextrins
  • Octoxynol
  • betadex
  • Thiabendazole