Abstract
Oriental medicine uses acupuncture at the GV01 acupoint with great success to treat diarrhea. It significantly reduced the colonic motility and inflammation in colitic rats. Naloxone pretreatment blocked these effects. The therapeutic effects of acupuncture at GV01 in colitis may involve endogenous opioid pathways.
Publication types
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Research Support, Non-U.S. Gov't
MeSH terms
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Acupuncture Points
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Acupuncture Therapy*
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Animals
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Colitis / chemically induced
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Colitis / pathology
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Colitis / therapy*
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Colon / drug effects
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Colon / enzymology
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Colon / pathology
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Disease Models, Animal
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Gastrointestinal Motility / drug effects
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Injections, Subcutaneous
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Male
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Naloxone / administration & dosage
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Naloxone / pharmacology
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Narcotic Antagonists / administration & dosage
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Narcotic Antagonists / pharmacology
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Peroxidase / metabolism
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Rats
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Rats, Sprague-Dawley
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Trinitrobenzenesulfonic Acid
Substances
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Narcotic Antagonists
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Naloxone
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Trinitrobenzenesulfonic Acid
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Peroxidase