Selective H3 receptor (H3R) blockade: broad efficacy in cognition and schizophrenia

Inflamm Res. 2005 Apr:54 Suppl 1:S23-4. doi: 10.1007/s00011-004-0410-1.
No abstract available

MeSH terms

  • Animals
  • Benzofurans / pharmacology*
  • Benzofurans / therapeutic use
  • Cognition / drug effects*
  • Cognition / physiology
  • Histamine Antagonists / pharmacology*
  • Histamine Antagonists / therapeutic use
  • Memory / drug effects
  • Memory / physiology
  • Mice
  • Mice, Inbred DBA
  • Models, Animal
  • Pyrrolidines / pharmacology*
  • Pyrrolidines / therapeutic use
  • Rats
  • Rats, Wistar
  • Receptors, Histamine H3 / metabolism*
  • Schizophrenia / drug therapy*
  • Schizophrenia / metabolism*

Substances

  • Benzofurans
  • Histamine Antagonists
  • Pyrrolidines
  • Receptors, Histamine H3
  • benzonitrile, 4-(2-(2-((2r)-2-methyl-1-pyrrolidinyl)ethyl)-5-benzofuranyl)-